| FML Forte (U.S.N.L.M.) | |
|---|---|
| Dosing | Shake. 1 drop 2 to 4 times daily. q4h in 1st 48 hrs if needed. Taper. |
| Chem Specs | fluorometholone alcohol 0.25% |
| Quantities | 5ml, 10ml, 15ml |
| Cost | Pred Forte 204.41 / 5ml |
| Class | Ketone, alcohol derived, fluorinated "soft" steroid. |
| Action | Anti-inflammatory. Inhibits phospholipase A2 blocking both arms of inflammatory cascade. |
| Usage | Indicated for inflammatory conditions of the anterior segment and adnexia. |
| Can cause significant IOP rise in as little as 1 week but somewhat less likely to do so than the other ketone based steroids so is sometimes used for longer term therapy. |
|
| Contraindications | Herpes simplex keratitis, vaccinia, varicella, and most other viral diseases of cornea and conjunctiva; tuberculosis; fungal diseases; acute purulent infections which may be masked or enhanced by the steroid; and hypersensitivity to any component of this preparation. |
| Pediatric use | > age 2 |
| Pregnancy | Category C. Embryocidal and teratogenic in rabbits at low multiples of the human ocular dose. |
| 0.25% FML Forte is no more efficacious than 0.1% FML. Fungal and bacterial overgrowth, cataract formation, globe perforation possible with long term use. |