| OSRX®   Timolol + Brimonidine + Dorzolamide + Bimatoprost | |
|---|---|
| Dosing | q.p.m. |
| Chem Specs | timolol 0.5%, brimonidine 0.1%, dorzolamide 2.0%, bimatoprost 0.01% |
| Quantities | 5ml, |
| Cost | 27.00.00 |
| Class | timolol: Non-selective beta-adrenergic receptor blocker. brimonidine: Relatively selective alpha-2 agonist. dorzolamide: Carbonic anhydrase inhibitor bimatatoprost: Prostaglandin analog (prodrug) |
| Usage | Easier to use and more cost effective than single-medication alternatives. |
| Contraindications |
timolol Bronchial asthma, a history of bronchial asthma, COPD, sinus bradycardia, second or third degree atrioventricular block, overt cardiac failure, cardiogenic shock. Numerous additional cautions listed here.
brimonidine neonates and infants (under the age of 2 years) Vascular insufficiency cautions listed here.
dorzolamide Sulfonamide hypersensitivity.
bimatoprost Bimatoprost hypersensitivity |
| Pediatric use | Bimatoprost: not recommended for patients below the age of 16 due to potential increased pigmentation with chronic use. |
| Pregnancy | Category C Dorzolamide is teratogenic in rabbits administered at 37x the level typically detected in human plasma after ocular administration. |
| Compounded in OSRX 503A/503B approved pharmacy. BAK preserved. |